This work is licensed under a Creative Commons Attribution 4.0 International License.
MAC-1-Sp4
General Information
DRACP ID DRACP06012
Peptide Name MAC-1-Sp4
Sequence GFGMⓍLKLⓍKKVL
Sequence Length 13
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Stapled Peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Chymotrypsin hydrolysis
Affinity Not available
Mechanism Resisting chymotrypsin hydrolysis
Nature Anticancer; Antimicrobial; Anti-hemolysis
Structure Information
Helicity Not available
Linear/Cyclic Cyclic (Stapled)
Disulfide/Other Bond Stapled: Ⓧ(5) and Ⓧ (9) are cross-linked by hydrocarbon stapling
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification Ⓧ=(2R)-2-amino-2-methyl-6-heptenoic acid
Chiral L
Physicochemical Information
Formula C59H100N14O10S
Absent amino acids ACDEHINPQRSTWY
Common amino acids KL
Mass 141182
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 5
Net charge 3
Boman Index 936
Hydrophobicity 60
Aliphatic Index 112.31
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN113896766A
Patent Title Novel anti-tumor cyclic peptide active molecule, preparation method and application
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.