MAC-1-Sp4

General Information


DRACP ID  DRACP06012

Peptide Name   MAC-1-Sp4

Sequence  GFGMⓍLKLⓍKKVL

Sequence Length  13

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Stapled Peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Chymotrypsin hydrolysis

Affinity  Not available

Mechanism  Resisting chymotrypsin hydrolysis

Nature  Anticancer; Antimicrobial; Anti-hemolysis



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic (Stapled)

Disulfide/Other Bond  Stapled: Ⓧ(5) and Ⓧ (9) are cross-linked by hydrocarbon stapling

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  Ⓧ=(2R)-2-amino-2-methyl-6-heptenoic acid

Chiral  L



Physicochemical Information


Formula  C59H100N14O10S

Absent amino acids  ACDEHINPQRSTWY

Common amino acids  KL

Mass  141182

Pl  11.1

Basic residues  3

Acidic residues  0

Hydrophobic residues  5

Net charge  3

Boman Index  936

Hydrophobicity  60

Aliphatic Index  112.31

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN113896766A

Patent Title  Novel anti-tumor cyclic peptide active molecule, preparation method and application

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.