This work is licensed under a Creative Commons Attribution 4.0 International License.
Tempor in-1CEa-Sp9
General Information
DRACP ID DRACP06028
Peptide Name Tempor in-1CEa-Sp9
Sequence FVⓍLKKIANⓍINSIFGK
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Stapled Peptides
Activity Information
Hemolytic Activity Low hemolysis
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antimicrobial
Structure Information
Helicity Not available
Linear/Cyclic Cyclic (Stapled)
Disulfide/Other Bond Stapled: Ⓧ(3) and Ⓧ (10) are cross-linked by hydrocarbon stapling
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification Ⓧ(3)=(2R)-2-amino-2-methyl-6-decanoic acid; Ⓧ(10)=(2R)-2-amino-2-methyl-6-heptenoic acid
Chiral L
Physicochemical Information
Formula C81H130N20O17
Absent amino acids CDEHMPQRTWY
Common amino acids IK
Mass 194162
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 8
Net charge 3
Boman Index -90
Hydrophobicity 52.94
Aliphatic Index 114.71
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN114605498A
Patent Title Stapled peptide antineoplastic active compound, pharmaceutical composition and application of stapled peptide antineoplastic active compound
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.