Tempor in-1CEa-Sp10

General Information


DRACP ID  DRACP06029

Peptide Name   Tempor in-1CEa-Sp10

Sequence  FVDⓍKKOANIⓍNSIFGK

Sequence Length  17

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Stapled Peptides



Activity Information


Hemolytic Activity  Low hemolysis

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antimicrobial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic (Stapled)

Disulfide/Other Bond  Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling

N-terminal Modification  Acetylation

C-terminal Modification  Amidation

Other Modification  Ⓧ(4)=(2R)-2-amino-2-methyl-6-decanoic acid; Ⓧ(11)=(2R)-2-amino-2-methyl-6-heptenoic acid

Chiral  L



Physicochemical Information


Formula  C73H111N19O17

Absent amino acids  CEHLMPQRTWY

Common amino acids  K

Mass  181237

Pl  10.51

Basic residues  3

Acidic residues  1

Hydrophobic residues  6

Net charge  2

Boman Index  -1946

Hydrophobicity  -16.47

Aliphatic Index  68.82

Half Life 
  /

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  4

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN114605498A

Patent Title  Stapled peptide antineoplastic active compound, pharmaceutical composition and application of stapled peptide antineoplastic active compound

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.