This work is licensed under a Creative Commons Attribution 4.0 International License.
TAT-LP8
General Information
DRACP ID DRACP06034
Peptide Name TAT-LP8
Sequence YGRKKRRQRRRLPDWHIPV
Sequence Length 19
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides MDM2 antagonistic
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target MDM2
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C112H185N43O24
Absent amino acids ACEFMNST
Common amino acids R
Mass 283920
Pl 12.51
Basic residues 9
Acidic residues 1
Hydrophobic residues 4
Net charge 8
Boman Index -10253
Hydrophobicity -201.58
Aliphatic Index 56.32
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 6990
Absorbance 280nm 388.33
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN114634551A
Patent Title Polypeptide and application thereof in preparation of anti-cancer drug for antagonizing combination of wild type p53 and MDM2
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.