DMS-PS1

General Information


DRACP ID  DRACP06037

Peptide Name   DMS-PS1

Sequence  GLWKSLFKNVGKAAGKAALNAVTDMVNQ

Sequence Length  28

UniProt ID  Not available

PubChem CID  Not available

Origin  South America frog Phy l lomeduasauvagi

Type  Native peptide

Classification

  

Cancer targeted peptides Induce apoptosis



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Inducing PC-3 cell apoptosis

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C131H215N37O37S

Absent amino acids  CEHIPRY

Common amino acids  A

Mass  341424

Pl  10.8

Basic residues  4

Acidic residues  1

Hydrophobic residues  13

Net charge  3

Boman Index  -1594

Hydrophobicity  3.57

Aliphatic Index  90.71

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  203.7

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN114835791A

Patent Title  Anticancer peptide DMS-PS1 of South America frog and application thereof

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.