This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DRACP ID DRACP06040
Peptide Name
Sequence KKCGIQDTNDKKQSD
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Agonist
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target IGFBP3
Affinity Not available
Mechanism The compound can be used as an agonist to competitively inhibit protein level interaction of PD-L1 and IGFBP3.
Nature Antucancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H118N22O27S
Absent amino acids AEFHLMPRVWY
Common amino acids K
Mass 195779
Pl 8.53
Basic residues 4
Acidic residues 3
Hydrophobic residues 1
Net charge 1
Boman Index -6491
Hydrophobicity -210
Aliphatic Index 26
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN115433287A
Patent Title Small molecule peptide and application thereof as agonist and in anti-cancer drugs
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.