General Information


DRACP ID  DRACP06040

Peptide Name  

Sequence  KKCGIQDTNDKKQSD

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Agonist



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  IGFBP3

Affinity  Not available

Mechanism  The compound can be used as an agonist to competitively inhibit protein level interaction of PD-L1 and IGFBP3.

Nature  Antucancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C68H118N22O27S

Absent amino acids  AEFHLMPRVWY

Common amino acids  K

Mass  195779

Pl  8.53

Basic residues  4

Acidic residues  3

Hydrophobic residues  1

Net charge  1

Boman Index  -6491

Hydrophobicity  -210

Aliphatic Index  26

Half Life 
  Mammalian:
  Yeast:
  E.coli:

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN115433287A

Patent Title  Small molecule peptide and application thereof as agonist and in anti-cancer drugs

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.