coloy(Trp-Val-Val-Ala-Ile-Phe)
General Information
DRACP ID DRACP06042
Peptide Name coloy(Trp-Val-Val-Ala-Ile-Phe)
Sequence WVVAIF
Sequence Length 6
UniProt ID Not available
PubChem CID Not available
Origin Frog fecal mildew
Type Native peptide
Classification
Cancer targeted peptides α-Glucosidase inhibitor
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target α-Glucosidase
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Trp1<--->Phe6
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C39H55N7O7
Absent amino acids CDEGHKLMNPQRSTY
Common amino acids V
Mass 82328
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 6
Net charge 0
Boman Index 2012
Hydrophobicity 276.67
Aliphatic Index 178.33
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 1100
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN115572324A
Patent Title Cyclochrome-valine-valine-propyl-bright-phenylalanine with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method of cyclochrome-valine-valine-propyl-bright-phenylalanine
Other Iinformation Not available
Other Published ID Not available