coloy(Trp-Val-Val-Ala-Ile-Phe)

General Information


DRACP ID  DRACP06042

Peptide Name   coloy(Trp-Val-Val-Ala-Ile-Phe)

Sequence  WVVAIF

Sequence Length  6

UniProt ID  Not available

PubChem CID  Not available

Origin  Frog fecal mildew

Type  Native peptide

Classification

  

Cancer targeted peptides α-Glucosidase inhibitor



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  α-Glucosidase

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  NCB: Trp1<--->Phe6

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C39H55N7O7

Absent amino acids  CDEGHKLMNPQRSTY

Common amino acids  V

Mass  82328

Pl  6.11

Basic residues  0

Acidic residues  0

Hydrophobic residues  6

Net charge  0

Boman Index  2012

Hydrophobicity  276.67

Aliphatic Index  178.33

Half Life 
  Mammalian: 2.8 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  1100

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN115572324A

Patent Title  Cyclochrome-valine-valine-propyl-bright-phenylalanine with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method of cyclochrome-valine-valine-propyl-bright-phenylalanine

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.