This work is licensed under a Creative Commons Attribution 4.0 International License.
coloy(Trp-Thr-Tyr-Ile-Phe)
General Information
DRACP ID DRACP06043
Peptide Name coloy(Trp-Thr-Tyr-Ile-Phe)
Sequence WTYIF
Sequence Length 5
UniProt ID Not available
PubChem CID Not available
Origin Frog fecal mildew
Type Native peptide
Classification
Cancer targeted peptides α-Glucosidase inhibitor
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target α-Glucosidase
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Trp1<--->Phe5
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C39H48N6O8
Absent amino acids ACDEGHKLMNPQRSV
Common amino acids FITWY
Mass 80037
Pl 6.09
Basic residues 0
Acidic residues 0
Hydrophobic residues 3
Net charge 0
Boman Index 752
Hydrophobicity 88
Aliphatic Index 78
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 6990
Absorbance 280nm 1747.5
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN115636869A
Patent Title Cyclic cyclo chrosurotyroisoleucine with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method of cyclic cyclo chrosurotyroisoleucine with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.