This work is licensed under a Creative Commons Attribution 4.0 International License.
coloy(Trp-Ala-Val-Ile-Leu)
General Information
DRACP ID DRACP06046
Peptide Name coloy(Trp-Ala-Val-Ile-Leu)
Sequence WAVIL
Sequence Length 5
UniProt ID Not available
PubChem CID Not available
Origin Frog fecal mildew
Type Native peptide
Classification
Cancer targeted peptides α-Glucosidase inhibitor
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target α-Glucosidase
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Trp1<--->Leu5
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C31H48N6O6
Absent amino acids CDEFGHKMNPQRSTY
Common amino acids AILVW
Mass 67230
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 5
Net charge 0
Boman Index 1802
Hydrophobicity 268
Aliphatic Index 234
Half Life
Mammalian: 2.8 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 1375
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN115651067A
Patent Title Cyclochrome-propyl-valine-isoleucine-leucine with hepatoma carcinoma cytotoxicity and alpha-glucosidase inhibitory activity and preparation method of cyclo-propyl-valine-isoleucine-leucine
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.