SEQ ID NO: 3 of Patent CN113135987A

General Information


DRACP ID  DRACP06050

Peptide Name   SEQ ID NO: 3 of Patent CN113135987A

Sequence  DPLVRRQRVQDLMAQMQGPYNFIQDSMLDFENQTLDPAIV

Sequence Length  40

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic (Derived from Caprin1)

Type  Synthetic peptide

Classification

  

Cancer targeted peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  G3BP1

Affinity  Not available

Mechanism  The compound can be competitively combined with the G3BP1 protein to specifically block the interaction between the Caprin1 and the G3BP1 protein and inhibit generation of stress particles so as to treat diseases related to the generation of SGs, such as tumors or neurodegenerative diseases.

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C204H323N57O64S3

Absent amino acids  CHKW

Common amino acids  Q

Mass  539018

Pl  4.01

Basic residues  3

Acidic residues  6

Hydrophobic residues  13

Net charge  -3

Boman Index  -8859

Hydrophobicity  -47

Aliphatic Index  85.25

Half Life 
  Mammalian: 1.1 hour
  Yeast: 3 min
  E.coli: >10 hour

Extinction Coefficient cystines  1490

Absorbance 280nm  38.21

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN113135987A

Patent Title  Active peptide derived from Caprin1 and application thereof

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.