This work is licensed under a Creative Commons Attribution 4.0 International License.
SEQ ID NO: 4 of Patent CN113135987A
General Information
DRACP ID DRACP06051
Peptide Name SEQ ID NO: 4 of Patent CN113135987A
Sequence DLMAQMQGPYNPIQDSMLDPENQTLDPAIV
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Synthetic (Derived from Caprin1)
Type Synthetic peptide
Classification
Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target G3BP1
Affinity Not available
Mechanism The compound can be competitively combined with the G3BP1 protein to specifically block the interaction between the Caprin1 and the G3BP1 protein and inhibit generation of stress particles so as to treat diseases related to the generation of SGs, such as tumors or neurodegenerative diseases.
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C143H226N36O50S3
Absent amino acids CFHKRW
Common amino acids DPQ
Mass 386324
Pl 3.17
Basic residues 0
Acidic residues 5
Hydrophobic residues 8
Net charge -5
Boman Index -4299
Hydrophobicity -47.33
Aliphatic Index 81.33
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 51.38
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN113135987A
Patent Title Active peptide derived from Caprin1 and application thereof
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.