This work is licensed under a Creative Commons Attribution 4.0 International License.
ALK-1
General Information
DRACP ID DRACP06065
Peptide Name ALK-1
Sequence CLHELLEHLHELLEHCLKKLLKLLKKLLKL
Sequence Length 30
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Targeted peptide conjugates
Activity Information
Hemolytic Activity Mouse red blood cells:Hemolysis rate=10%=50μM
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys1<--->Cys16
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C170H294N44O39S2
Absent amino acids ADFGIMNPQRSTVWY
Common amino acids L
Mass 416010
Pl 8.81
Basic residues 10
Acidic residues 4
Hydrophobic residues 14
Net charge 6
Boman Index -774
Hydrophobicity 26.67
Aliphatic Index 182
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 125
Absorbance 280nm 4.31
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID CN110862458A
Patent Title Combined peptide with acid-activated anti-tumor activity and clinical application of combined peptide
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.