IDP-Lb04

General Information


DRACP ID  DRACP06164

Peptide Name   IDP-Lb04

Sequence  SKAⓍKVVILSⓍALEYL

Sequence Length  16

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer targeted peptides Stapled Peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Cyclic(stapled)

Disulfide/Other Bond  Stapled: Ⓧ(4) and Ⓧ (11) are cross-linked by hydrocarbon stapling

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  Ⓧ(4)=2-amino-2-methyl-6-decanoic acid; Ⓧ(11)=2-amino-2-methyl-9-heptenoic acid

Chiral  L



Physicochemical Information


Formula  C72H120N16O18

Absent amino acids  CDFGHMNPQRTW

Common amino acids  L

Mass  176558

Pl  9.26

Basic residues  2

Acidic residues  1

Hydrophobic residues  8

Net charge  1

Boman Index  653

Hydrophobicity  85.63

Aliphatic Index  146.25

Half Life 
  /

Extinction Coefficient cystines  1490

Absorbance 280nm  99.33

Polar residues  3

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID CN111511761A

Patent Title  Anticancer Peptides

Other Iinformation  Not available

Other Published ID  Not available




DRACP is developed by Dr.Zheng's team.